Our research group takes a top-down approach to create micrometer-scale, electric signal-controlled microrobots that are compatible with integrated circuits. These microrobots are being adapted for specific biomedical applications, with each subproject designed to replicate one of the essential capabilities of a micro-surgeon.

Currently, we are focused on developing microrobots with the following abilities:

• Cell/tissue manipulation: Effective manipulation of cells and tissues requires microrobots with multiple degrees of freedom and sufficient strength. This subproject focuses on the structural design of microrobots so that it can manipulate cell and tissue in various ways, and the conformal morphing of microrobots towards the geometry of target cell or tissue.

• Tumor organoids treatment: Treating tumor organoids requires microrobots to detect tumors autonomously and either deliver drugs or physically treat the affected area. This subproject focuses on the integration of biochemical sensor with the microrobot and locomotion or shape-morphing capability that enables the microrobot to move towards the tumor organoids.

• Biomechanics characterization: Biomechanics is critical to cell or tissue behaviors, which influences macroscopic health issues include wound healing, bone regeneration, fetus development, etc. Characterization of biomechanics requires precise force exertion and measurement. This subproject focuses on the integration of strain and force sensor with the microrobot and the on-board close loop control of the micro-robotic motion.

• Precise drug delivery: Efficient drug delivery through vessels or oral pathways demands microrobots capable of swimming and overcoming fluid resistance. This subproject focuses on the swimming mechanism design and strength characterization of the microrobot, as well as the drug storage and release mechanism design.

By advancing these capabilities, we aim to create versatile, intelligent microrobots that can fulfill the vision of the micro-surgeon and open new frontiers in medicine